Vol. 10, Special Issue 11 (2021)

Author(s):
Gaurav Charaya, Parveen Goel, Jasleen Kaur, Sunil Punia, Preeti Bagri and Yudhbir Singh

Abstract:
The present study was conducted to elucidate the lipid peroxidation level, antioxidant status and haemato-biochemical alteration in cross bred suffering from tropical theileriosis. An organized farm of 40 cross bred cattle with a history of theileriosis was screened for disease on the basis of clinical signs and conventional microscopy. All the animals were clinically examined for mucous membrane, rectal temperature and swelling of lymph nodes. Seven animals found positive for characteristics piroplasm on microscopic examination of Geimsa stained smear and showing typical signs of disease were considered positive whereas fifteen other animals not showing signs and negative in blood smear was considered as control group. Lipid peroxidation was evaluated by calculating plasma Malondialdehyde levels and antioxidant status was evaluated by estimating plasma superoxide dismutase and plasma glutathione reductase. MDA level and SOD activity was found significantly increased whereas GSH activity was found to be significantly increased clearly indicating theileriosis impart oxidative stress. Following therapy with buaparvaquone non-significant changes were observed as no antioxidant was added in therapy. Therefore, it can be concluded that parasite impart oxidative stress and to decrease the level antioxidants must be added along with drug of choice.