Vol. 10, Special Issue 12 (2021)

Author(s):
QU Nazir, MI Yatoo, M Shaheen, A Muhee, OR Parray and IU Haq

Abstract:
Present study was conducted to study/explore the effect of various therapeutic regimes on the oxidative indices in mycoplasma affected goats. Thirty (N=30) clinically mycoplasma affected goats were taken and allotted to three test groups viz., Group I, II and III and were treated with different antimicrobials with each group having 10 animals (n=10). Group I was treated with tylosin @ 20 mg/kg, Group II with oxytetracycline @10 mg/, and Group III was treated levofloxacin @ 1.5 mg/kg body weight IM. Supportive medicines given with antimicrobials included flunexin meglumine @ 1.1 mg/kg and chlorpheneramine @ 0.5 mg/kg intramuscularly daily for three days in all test groups. Results indicated that at the 0^th hour of the experimental trial, there were significant (P≤0.05) alterations in oxidative indices/values of all the three test groups compared to healthy control. With course of the trial, significant (P≤0.05) changes were observed in total oxidant status(TOS) and total anti-oxidant status (TAS) in group I alone indicating Tylosin gives better results compared to other antimicrobial agents.